Minimal Cells: Design, Construction, Biotechnological Applications by Alvaro R.

Description: Minimal Cells: Design, Construction, Biotechnological Applications by Alvaro R. Lara, Guillermo Gosset Estimated delivery 3-12 business days Format Paperback Condition Brand New Description This book provides a comprehensive overview of the design, generation and characterization of minimal cell systems. Publisher Description This book provides a comprehensive overview of the design, generation and characterization of minimal cell systems. Written by leading experts, it presents an in-depth analysis of the current issues and challenges in the field, including recent advances in the generation and characterization of reduced-genome strains generated from model organisms with relevance in biotechnology, and basic research such as Escherichia coli, Corynebacterium glutamicum and yeast. It also discusses methodologies, such as bottom-up and top-down genome minimization strategies, as well as novel analytical and experimental approaches to characterize and generate minimal cells. Lastly, it presents the latest research related to minimal cells of serveral microorganisms, e.g. Bacillus subtilis.The design of biological systems for biotechnological purposes employs strategies aimed at optimizing specific tasks. This approach is based on enhancing certain biological functions while reducing other capacities that are not required or that could be detrimental to the desired objective. A highly optimized cell factory would be expected to have only the capacity for reproduction and for performing the expected task. Such a hypothetical organism would be considered a minimal cell. At present, numerous research groups in academia and industry are exploring the theoretical and practical implications of constructing and using minimal cells and are providing valuable fundamental insights into the characteristics of minimal genomes, leading to an understanding of the essential gene set. In addition, research in this field is providing valuable information on the physiology of minimal cells and their utilization as a biological chassis to which useful biotechnological functions can be added. Author Biography Alvaro R. Lara was awarded a PhD in Biochemical Sciences from the Universidad Nacional Autónoma de México in 2007. He is currently an Associate Professor at the Universidad Autónoma Metropolitana. His research focuses on biological engineering, biochemical engineering and biomanufacturing using microbial and mammalian cells. He has published more than 40 research articles and book chapters, as well as 3 patents. Dr. Lara is member of the editorial board of the journals Bioprocess and Biosystems Engineering and Microbial Cell Factories.Guillermo Gosset was awarded a Ph.D. degree in Biotechnology from the Universidad Nacional Autónoma de México (UNAM) in 1993. Since 1988 he has been a research scientist at the Biotechnology Institute/UNAM. His main research interests are related to metabolic pathway engineering and microbial physiology. Gossets work has appeared in more than 121 publications and been included in 8 patents. Several of these publications are utilized as examples in textbooks in the field of metabolic engineering. His industrial experience includes two years as a visiting scientist at Genencor International (Palo Alto, U.S.A.) and one year at Metabolic Explorer (Clermont-Ferrand, France). He is member of the editorial board of the Journal of Molecular Microbiology and Biotechnology, where he has been the Senior Editor since 2006. He has also been the Associate Editor of Microbial Cell Factories since 2014. Details ISBN 3030318990 ISBN-13 9783030318994 Title Minimal Cells: Design, Construction, Biotechnological Applications Author Alvaro R. Lara, Guillermo Gosset Format Paperback Year 2021 Pages 230 Edition 1st Publisher Springer Nature Switzerland AG GE_Item_ID:137807405; About Us Grand Eagle Retail is the ideal place for all your shopping needs! With fast shipping, low prices, friendly service and over 1,000,000 in stock items - you're bound to find what you want, at a price you'll love! Shipping & Delivery Times Shipping is FREE to any address in USA. Please view eBay estimated delivery times at the top of the listing. Deliveries are made by either USPS or Courier. We are unable to deliver faster than stated. International deliveries will take 1-6 weeks. NOTE: We are unable to offer combined shipping for multiple items purchased. This is because our items are shipped from different locations. 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